Top 10 Immune Support Supplements Of 2024

The top immune support supplements currently on the market are designed to offer support for a healthy immune system. With a commitment to quality, transparency, and value, I aimed to find top-tier immune support supplements that are safe and can exceed expectations.

I’ve narrowed down the Top 10 Immune Support Supplements in 2024, highlighting their unique features, benefits, and what sets them apart in the competitive market. By the end of this article, you’ll have all the information you need to make an informed decision and select the perfect immune support supplements for your wellness journey. 

NWI Times Review Roundup 

1. Best Overall Immune Support Supplements – Sunny Within Daily Defense 

2. Best Fast Acting Immune Defense – Organifi Critical Immune

3. Best Immune Support Supplement With High-Quality Ingredients – Research Verified Immune Booster

4. Best Vegetarian Immune Support Supplement – Stonehenge Health Dynamic Immunity

5. Best Immune Support Supplement With Zinc – Source Naturals Wellness Formula

6. Best Immune Support Supplement For Multi-System Help – Nature’s Way SystemWell Ultimate Immunity

7. Best Immune Support Supplement Spray – GlutaDose Wellness

8. Best Fully Organic Immune Support Supplement- Wakunaga Overall Immune Health

9. Best B Complex Immune Support Supplement – Nature Made Super B Energy

10. Best Multivitamin Immune Support Supplement – Thorne Basic Nutrients 2/Day

Best Immune Support Supplements


How We Chose The Best Immune Support Supplements

In my quest to identify the best immune support supplements, I focused on key indicators that reflect ingredient efficacy, third-party testing, customer reviews, and brand reputation. Here’s a detailed breakdown of my selection criteria:

Third-Party Lab Testing

Third-party lab testing is a critical aspect of ensuring the quality, safety, and efficacy of immune support supplements. It involves independent testing by external laboratories that are not affiliated with the manufacturer. This process helps verify that the product meets its label claims and is free from contaminants. Here’s a comprehensive overview of third-party lab testing for immune support supplements:

  • Verification of Claims Confirms that the supplement contains the ingredients and dosages listed on the label. Ensures that the product delivers the claimed health benefits.
  • Safety Assurance: Detects harmful substances such as heavy metals, pesticides, or microbial contaminants. Verifies that the product is free from adulterants and impurities.
  • Quality Control: Ensures that the product is manufactured consistently according to the quality standards. Confirms that the supplement meets industry regulations and standards.

Made In The US 

When looking for immune supplements made in the U.S., it’s important to focus on products that adhere to high manufacturing standards and quality controls. Supplements made in the U.S. are often subject to rigorous regulations and quality assurance processes. Here’s a list of reputable U.S.-based immune supplements, along with some general guidelines on what to look for:

  • Look for Quality Certifications: Choose supplements that are certified by third-party organizations like the U.S. Pharmacopeia (USP), NSF International, or Good Manufacturing Practices (GMP) to ensure quality and safety.
  • Check Ingredient Sourcing: Ensure that the ingredients are sourced responsibly and that the product contains no harmful additives or contaminants.
  • Read Labels Carefully: Review the ingredient list, dosage instructions, and any potential allergens or fillers.

Strict Adherence to Guidelines (Including Non-GMO ingredients)

Strict adherence to guidelines for immune supplements involves ensuring that the products meet high standards of quality, safety, and effectiveness. Here’s a comprehensive guide to help you understand what to look for in immune supplements that adhere to strict guidelines, including non-GMO ingredients:

  • Good Manufacturing Practices (GMP): Ensure the supplement is manufactured in facilities that follow GMP standards. This certification indicates that the product is produced under strict quality controls and is consistently produced and controlled according to quality standards.
  • U.S. Pharmacopeia (USP): USP verification ensures that the supplement contains the ingredients listed on the label, in the declared potency and amounts, and does not contain harmful levels of contaminants.
  • NSF International: Look for supplements with NSF certification, which verifies that the product meets public health and safety standards.

Multiple Reviews + Trust Badges (Return Options, Easy Shipping, etc.)

When evaluating immune supplements, multiple reviews and trust badges are essential for ensuring that you are purchasing a high-quality product from a reputable brand. Here’s how you can assess these aspects and why they are important:

  • Verified Purchases: Focus on reviews from verified buyers to ensure authenticity.
  • Detailed Feedback: Look for reviews that provide specific details about the product’s effectiveness, taste, and any side effects.
  • Overall Ratings: Consider the overall rating of the product, but also delve into individual reviews to understand the context.

Pricing Guide

$ – Under 39.99

$$ $40.00-59.99

$$$ – $60.00+

NWI Times Picks For The Top Immune Support Supplements

1. Best Overall Immune Support Supplements

SunnyWithIn Daily Defense Pineapple Passion Fruit

Sunny WithIn Daily Defense
Sunny WithIn Product Scorecard

  • Price: $$
  • Type: Immune Support Supplement
  • Organic: Yes
  • Best For: Supports the health of your cells, immune system, and skin.
  • Pros: Organic, active ingredients, supports immune system, third-party tested
  • Cons: Might be expensive for some.

Contains Organic Avocado Oil

Sunny Within’s Daily Defense immunity supplement is enriched with organic avocado oil, a powerhouse ingredient known for its anti-inflammatory and antioxidant properties. This nutrient-dense oil supports the absorption of fat-soluble vitamins, enhancing the overall effectiveness of the supplement’s immune-boosting ingredients. Organic avocado oil also contributes to heart health and skin vitality, making it an essential component in fortifying your body’s natural defenses while promoting overall wellness.

SunnyWithIn Daily Defense

Why Sunny Within Is The Best Overall Product

Sunny WithIn is the best overall immune support supplements due to its impressive list of active ingredients including bee propolis to support healing and microbial protection, quercetin for antioxidant and immunity support, vitamin C  for immune system support and skin health, vitamin D for immune support, calcium absorption, and bone health, and zinc for immune system support and skin health. 

2.  Best Fast Acting Immune Defense

Organifi Critical Immune


Organifi Critical Immune
Organifi Product Scorecard

  • Price: $ – $$$
  • Type: Immune Support Supplement
  • Organic: Yes
  • Best For: Enhancing immunity, combating oxidative stress, and more.
  • Pros: Fast-acting
  • Cons: Hard to judge efficacy, may not provide long-lasting relief. 

Why Organifi Has The Best Fast-Acting Immune Defense

Organifi Critical Immune is recognized for having one of the best fast-acting immune defense supplements due to its advanced formulation, high potency, and the use of quality ingredients. The supplement’s fast absorption and effective combination of vitamins, minerals, and herbal extracts contribute to its quick action in supporting the immune system. Positive user feedback, transparency in quality control, and the synergistic effects of its ingredients reinforce its reputation as a top choice for rapid immune support.

What Our Reviewers Say

About Organifi Critical Immune

  • Every time I feel like I’m getting sick I start taking this and I swear it prevents me from any full blown viruses and colds! Sometimes I’ll take it preventatively if I know I’m traveling or going to be in big crowds. Works great!!” – Amanda M., Verified Buyer. 
  • “With my babies being sick all the time from daycare this stuff really helps me bounce back and keep going.” – Mayra R., Verified Buyer. 

3. Best Immune Support Supplement With High-Quality Ingredients

Immune Booster


Research Verified Immune Booster
Research Verified Product Scorecard

  • Price: $$ – $$$
  • Type: Immune Support Supplement
  • Organic: Not specified
  • Best For: Providing comprehensive immune support. 
  • Pros: Product transparency
  • Cons: Can be expensive for some, results may vary. 

Why Research Verified Has The Best Immune Support Supplement With High-Quality Ingredients

Research Verified Immune Booster is considered one of the best immune support supplements due to its high-quality ingredients, transparency, and science-based formulation. The supplement is made with premium, evidence-based ingredients, undergoes third-party testing, and is free from artificial additives. Its focus on bioavailability, clean formulation, and positive user feedback highlights its effectiveness and reliability in providing comprehensive immune support.

4. Best Vegetarian Immune Support Supplement

Stonehenge Health Dynamic Immunity
Stonehenge Health Organics Product Scorecard

  • Price: $ – $$$
  • Type: Immune Support Supplement
  • Organic: Not specified
  • Best For: For individuals seeking to enhance their immune system, especially during times of increased exposure to pathogens like during cold and flu season.
  • Pros: Includes a blend of vitamins, minerals, and extracts for immune support, plant-based ingredients.
  • Cons: Varying price point, large capsule size.

Why Stonehenge Health Has The Best Vegetarian Immune Support Supplement

Stonehenge Health Dynamic Immunity is considered the best vegetarian immune support supplement due to its use of high-quality, plant-based ingredients, comprehensive nutrient profile, and transparency in labeling. It is non-GMO, free from common allergens, and avoids artificial additives, making it suitable for a wide range of dietary preferences. The supplement’s effectiveness, coupled with third-party testing and ethical practices, makes it a reliable choice for vegetarians seeking to support their immune health.

What Our Reviewers Say

About Stonehenge Health Dynamic Immunity

  • “My sister is a nurse, and I asked her how she has managed to stay so healthy with all she comes in contact with at work. She told me she uses Stonehenge Health’s Dynamic Immunity and that I should give it a try. In the 5 months since I started taking Dynamic Immunity, I have not been sick. I’m in Kentucky, and this state is notorious for pollen allergies. Since I started taking these pills, I haven’t had any of my usual sinus allergies. The pills are also easy to swallow too. From now on, I will always have a bottle on hand.” – Melvin S.
  • “After a recent battle with the flu, I decided I needed to get on an immune system boosting routine. I chose Stonehenge Health Dynamic Immunity based on the amount of elderberry extract and the other ingredients. These supplements come with a 90-day return policy, which also influenced my decision to go with Dynamic Immunity. I know that other immune system brands are less expensive but be sure to read the labels. Others don’t have nearly as much elderberry extract, so end up being more expensive in the long run.” – Shamari K. 

5. Best Immune Support Supplement With Zinc

Source Naturals Wellness Formula
Source Naturals Product Scorecard

  • Price: $ – $$
  • Type: Immune Support Supplement
  • Organic: Not specified
  • Best For: Enhancing immune support. 
  • Pros: Number of capsule options available.
  • Cons: May have potential allergens, limited information about product.

Why Source Naturals Has The Best Immune Support Supplement With Zinc

Source Naturals Wellness Formula is considered one of the best immune support supplements with zinc due to its comprehensive formulation that includes effective dosages of zinc, along with other key vitamins, minerals, and herbal extracts. Its high-quality ingredients, enhanced absorption, transparency, and positive user feedback contribute to its reputation as an effective immune support supplement. The inclusion of zinc supports various aspects of immune health, making it a reliable choice for those seeking to bolster their immune system.

What Our Reviewers Say

About Source Naturals Wellness Formula:

  • “Whenever I get that tickle in my throat, I will pop 3-7 Wellness Pills throughout the day. I swear by them; they are magic.” – Sailor Bockius, Amazon Customer
  • “Have used this product for years, and will continue to do so.” – MGF, Amazon Customer

6. Best Immune Support Supplement For Multi-System Help

Nature’s Way SystemWell Ultimate Immunity
Nature’s Way Product Scorecard

  • Price: $
  • Type: Immune Support Supplement
  • Organic: Not specified
  • Best For: Supporting the five essential aspects of health: respiratory, digestive, systemic, circulatory, and cellular health
  • Pros: Comprehensive formula, responsible packaging, synergistic blend
  • Cons: Organic not specified, digestive issues possible

Why Nature’s Way Has The Best Immune Support Supplement For Multi-System Help

Nature’s Way SystemWell Ultimate Immunity is recognized as one of the best immune support supplements for its comprehensive and multi-system approach to health. Its diverse formula, synergistic blend of ingredients, and the trusted reputation of the Nature’s Way brand make it a standout choice. The supplement not only supports immune function but also promotes overall wellness, providing a holistic approach to health.

What Our Reviewers Say

About Nature’s Way SystemWell Ultimate Immunity Supplements: 

  • “I always have sinus problems and easily catch flue and cold, these tablets do magic, of I take them I’m stronger than ever, no more flue, no more cold, no sinus problems. Love love love these. Lifesaver!” – aveilarum
  • “I’ve been using this product for several years and swear by it for reducing the severity of colds and flu, and even preventing them altogether.” – Jen F.

7.  Best Immune Support Supplement Spray

GlutaDose Wellness
GlutaDose Product Scorecard

  • Price: $$
  • Type: Glutathione Supplement
  • Organic: Not specified
  • Best For: Those looking for immune system help to fight viral or bacterial infections and to reduce the discomfort of colds.
  • Pros: Easy to administer, made in the USA in a cGMP & FDA-compliant pharmaceutical facility
  • Cons: Liquid formula might not be right for some users, can be expensive for some users

Why GlutaDose Has The Best Immune Support Supplement Spray

GlutaDose Wellness offers a unique and effective approach to immune support through its spray formulation. The convenience, enhanced bioavailability, and rapid absorption make it a standout choice for those seeking a practical and efficient way to boost their immune system. The high-quality ingredients and easy administration contribute to its reputation as a top option for immune support in spray form.

What Our Reviewers Say

About GlutaDose Wellness Supplements: 

  • “I’ve used this natural immune booster several times, and I’m really impressed with how well it works. I’ve been getting sick less often, and when I do get sick, my symptoms are milder and I recover more quickly. The product is made with a blend of natural ingredients that have been shown to boost my immune function. It’s easy to take with a great flavor. I’m so glad I found this product. It’s a natural and effective way to boost my immune system and stay healthy without the traditional chemical medicines.” – M. Naranjo, Amazon Review
  • “This is a good product. It does seem to work as advertised. Furthermore, the cost is relatively reasonable. All in all this is a good product. I’d buy this again and would recommend it to anyone interested in it.” – DDS24

Best Fully Organic Immune Support Supplement

Wakunaga Overall Immune Health
Wakunaga Product Scorecard

  • Price: $
  • Type: Immune Support Supplement
  • Organic: Yes
  • Best For: Supporting immune function and providing antioxidant protection.
  • Pros: Non-GMO, gluten free, variety of capsule amounts to choose from, relatively inexpensive
  • Cons: Contains aged garlic extract which may be unsuitable for users, possible side effects

Why Wakunaga Has The Best Fully Organic Immune Support Supplement

Wakunaga Overall Immune Health stands out as a top choice for those seeking a fully organic immune support supplement due to its organic certification and use of certified organic ingredients, and its lack of synthetic chemicals. 

What Our Reviewers Say

About Wakunaga Overall Immune Health Supplements: 

  • “I am a big fan of your product. I have found it to be very helpful with sinus/cold issues, and totally believe it has antiviral properties. I am going to my local store to stock up this week. Thanks for all you do Kyolic!” – Kathy Kelly 
  • “I started getting what felt like a cold. Since I was going to be visiting my aging parents in a few days, I started taking the product. Within 12 hours, I could tell the symptoms were virtually gone. I took it for another couple days, and haven’t had any trouble since. It is easy to use, and works quickly. I will be sure to use it again if I have any symptoms coming on.” – Johnna Mellor

Best B Complex Immune Support Supplement

Nature Made Super B Energy
Nature Made Product Scorecard

  • Price: $
  • Type: B Complex Immune Support Supplement
  • Organic: Not specified
  • Best For: Those looking for support with nervous system function.
  • Pros: No preservatives or synthetic dyes, one daily softgel.
  • Cons: Organic not specified, results can vary among individuals.

Why Nature Made Has The Best B Complex Immune Support Supplement

Nature Made Super B Energy stands out as one of the best B-complex supplements for immune support due to its comprehensive B vitamin blend in balanced dosages. This supplement contains vitamins like B6 and B12 that are crucial for immune health. 

What Our Reviewers Say

About Nature Made Super B Energy Supplements: 

  • “I love it. It gives the energy I needed. I take one every day to help my body.” – Darwin
  • “These are football-shaped soft gels, less than a half inch in length. I have difficulty swallowing most pills, but these are easy to swallow.” – Sinead Green

10. Best Multivitamin Immune Support Supplement

Thorne Basic Nutrients 2/Day
Thorne Product Scorecard

  • Price: $
  • Type: Multivitamin Supplement
  • Organic: Not specified
  • Best For: Those looking for a comprehensive supplement that contains key nutrients for foundational support.
  • Pros: Wide range of vitamins and minerals included, free from common allergens including gluten, dairy, and soy.
  • Cons: Sensitivity to ingredients, nutrient overlap in diet.

Why Thorne Has The Best Multivitamin Immune Support Supplement

Thorne Basic Nutrients 2/Day stands out as the best multivitamin for immune support due to the essential vitamins and minerals it possesses for immune function. The supplement does not contain artificial additives, and has a clean and natural formulation. 

What Our Reviewers Say

About Thorne Basic Nutrients 2/Day Supplements: 

  • Love the Thorne quality, and you only need to take 2 or sometimes just 1.” – David A. 
  • “This is a game changer, especially when I’m recovering from any cold/flu. This helped me keep going and shortened my sick days.” – Nafia M. 

What Are The Potential Benefits Of Immune Support Supplements?

Enhanced Immune Function

Many immune support supplements contain vitamins, minerals, and herbs that help boost the immune system, making it more effective at defending against pathogens such as viruses and bacteria. Ingredients like Vitamin C, Vitamin D, and Zinc are known to enhance the body’s immune response and support the production of white blood cells, which are crucial for fighting infections.

Reduced Frequency Of Illness

Regular use of immune support supplements may reduce the frequency and severity of common colds, flu, and other infections by strengthening the body’s defenses.

Faster Recovery

Some supplements can aid in faster recovery from illnesses by supporting the body’s natural healing processes and improving overall vitality and strength.

Increased Energy Levels

A strong immune system is better equipped to handle stressors, potentially leading to increased energy levels and reduced feelings of fatigue.

How to Shop For The Best Immune Support Supplements? 

Shopping for the best immune support supplements involves careful consideration of several factors to ensure you select high-quality products that meet your needs. Here’s a step-by-step guide on how to shop effectively:

  1. Identify Your Needs: Determine your specific health goals and needs. Are you looking to boost general immunity, support recovery from illness, or manage chronic conditions? Consider any dietary restrictions, allergies, or preferences (e.g., vegan, gluten-free, organic).
  2. Research Key Ingredients: Look for supplements that contain well-researched and proven ingredients such as Vitamin C, Vitamin D, Zinc, Elderberry, Echinacea, and Probiotics. Choose products that combine complementary ingredients for a broader range of benefits.
  3. Check for Quality Assurance: Opt for supplements that have been tested by independent third parties for purity, potency, and safety. Look for certifications such as NSF, USP, or GMP to ensure the product meets high-quality standards.
  4. Verify Ingredient Sources: Ensure that the ingredients are sourced from reputable suppliers and are free from contaminants and harmful additives. If you prefer natural products, choose supplements that are organic and non-GMO.
  5. Read Labels and Dosage Instructions: Check the supplement label for a clear list of ingredients, their amounts, and any other additives or fillers. Follow the recommended dosage instructions to avoid overconsumption or underconsumption.
  6. Evaluate Product Form: Supplements come in various forms, such as capsules, tablets, powders, gummies, or liquids. Choose a form that you find convenient and easy to take. Consider supplements with enhanced delivery systems (e.g., liposomal or timed-release formulations) for better absorption.

Are There Any Side Effects Of Immune Support Supplements?

Immune support supplements can be beneficial for enhancing immune function, but like any supplement, they can potentially have side effects. 

Be aware of common side effects such as digestive issues, allergic reactions, headaches, insomnia, and interactions with other medications. 

There are also ingredient-specific side effects that you should be aware of from the active ingredients in these immune support supplements. Before taking any supplement, be sure to consult with your healthcare provider and adhere to the recommended dosage and usage instructions to minimize the risk of side effects. 

How I Wrote This:

Creating a list of the top 10 immune support supplements of 2024 required me to conduct thorough research and evaluations to ensure that only the best products made it into this curated selection. Key considerations included ingredient efficacy, third-party testing, customer reviews, and brand reputation.

My exploration spanned from well-established to up-and-coming brands, meticulously examining customer feedback, product details, and third-party lab tests for utmost transparency and trustworthiness. The quality of the immune support supplements, particularly those that have immune-boosting properties, was a crucial determinant in evaluating the overall effectiveness of the supplements.

Through this meticulous process, I am confident that the top 10 immune support supplements of 2024 presented in this listicle are not only reliable and effective but also tailored to meet the unique needs of consumers seeking advanced immune support benefits.

Frequently Asked Questions About Best Immune Support Supplements

What are the top 10 immune support supplements of 2024?

The top 10 immune support supplements making waves in 2024 include a blend of traditional vitamins, minerals, and some unexpected but effective ingredients. Look out for Vitamin C, Vitamin D, Zinc, Elderberry, Probiotics, Echinacea, Garlic, Turmeric, Selenium, and specialized CBD products. Companies like FOCL are pioneering the way with Premium CBD-based supplements formulated with organically grown hemp and nature’s finest to bolster your immune system.

How do immune support supplements work?

Immune support supplements work by providing your body with essential nutrients and compounds that aid its natural defense mechanisms. Vitamins like C and D, for instance, play a crucial role in supporting the immune system’s barriers against pathogens, while minerals like zinc are critical for immune cell function. Herbal supplements and probiotics help in different ways, such as boosting gut health, which is closely linked to immune function. CBD products, particularly those developed by trusted brands like FOCL, support the immune system by helping to manage inflammation and stress, factors known to impact immune health.

Are there any side effects associated with immune support supplements?

Like any supplement, immune support products can have side effects, although these are generally mild when the supplements are taken as directed. Exceeding recommended doses, especially of vitamins and minerals, can lead to adverse effects. High doses of Vitamin C, for example, might cause gastrointestinal upset, while excessive zinc could interfere with copper absorption. It’s always recommended to discuss any new supplement with a healthcare provider, especially if you have underlying health conditions or are taking medications.

Can immune support supplements prevent colds and flu?

While no supplement can offer 100% protection against colds and flu, various immune support supplements can significantly reduce your risk or lessen the severity and duration of these illnesses. Supplements rich in vitamins, minerals, and plant-based ingredients can bolster your body’s defenses, making it better equipped to fight off infections. Consistent use of high-quality supplements, like those from FOCL, in tandem with a healthy lifestyle, can be a game-changer when it comes to preventing colds and flu.

What ingredients should I look for in an immune support supplement?

The essential ingredients to look for in an immune support supplement include Vitamins C and D, Zinc, and Selenium for their scientifically backed immune-boosting properties. Additionally, herbal components like Elderberry, Echinacea, and Garlic are well-regarded for their effectiveness in supporting immune health. Probiotics are another key ingredient, vital for gut health, which plays a significant part in the immune function. Innovative products may also include CBD for its potential to manage inflammation and stress, thereby indirectly supporting the immune system.